Temple (November 9, 2021)
All-Time Series: First meeting 2021-22
Record vs Temple on the road: Series tied 0-0
Current Streak: N/A
First Meeting: 2021-22
Last Meeting: N/A

Kent State (November 14, 2021)
All-Time Series: Saint Francis leads 3-1
Record vs Kent State on the road: Series tied at 1
Current Streak: Saint Francis won 2
First Meeting: Kent State (85-52) 2006-07
Last Meeting: Saint Francis (67-64) 2020-21

West Virginia (November 16, 2021)
All-Time Series: West Virginia leads 6-0
Record vs on the road: West Virginia leads 6-0
Current Streak: West Virginia won 6
First Meeting: West Virginia (74-68) 2004-05
Last Meeting: West Virginia (74-45) 2019-20

Longwood (November 20, 2021)
All-Time Series: Saint Francis leads 2-1
Record vs Longwood at home: Saint Francis leads 1-0
Current Streak: Saint Francis won 1
First Meeting: Saint Francis (65-55) 2007-08
Last Meeting: Saint Francis (91-88) 2018-19

Coppin State (November 28, 2021)
All-Time Series: Saint Francis leads 2-0
Record vs Coppin State on the road: Saint Francis leads 1-0
Current Streak: Saint Francis won 2
First Meeting: Saint Francis (77-67) 2010-11
Last Meeting: Saint Francis (69-67) 2011-12

Bucknell (December 1, 2021)
All-Time Series: Bucknell leads 1-0
Record vs Bucknell on the road: Series tied 0-0
Current Streak: Bucknell won 1
First Meeting: Bucknell (70-46) 2018-19
Last Meeting: Bucknell (70-46) 2018-19 

La Salle (December 4, 2021)
All-Time Series: La Salle leads 1-0
Record vs La Salle at home: Series tied 0-0
Current Streak: La Salle won 1
First Meeting: La Salle (76-68) 2020-21
Last Meeting: La Salle (76-68) 2020-21
Last Saint Francis Win: NA

Toledo (December 8, 2021)
All-Time Series: Toledo leads 3-1
Record vs Toledo on the road: Toledo leads 2-1
Current Streak: Toledo won 3
First Meeting: Toledo (82-79 ot) 2004-05
Last Meeting: Toledo (74-66) 2017-18

Duquesne (December 11, 2021)
All-Time Series: Duquesne leads 31-10
Record vs Duquesne on the road: Duquesne leads 14-5
Current Streak: Duquesne won 11
First Meeting: Saint Francis (49-34) 1968-69
Last Meeting: Duquesne (69-67) 2020-21

Georgia (December 19, 2021)
All-Time Series: Georgia leads 1-0
Record vs Georgia on the road: Georgia leads 1-0
Current Streak: Georgia won 1
First Meeting: Georgia (98-66) 1995-96
Last Meeting: Georgia (98-66) 1995-96

Jacksonville State (December 21, 2021)
All-Time Series: First meeting 2021-22
Record vs Jacksonville State on the road: Series tied 0-0
Current Streak: N/A
First Meeting: 2021-22
Last Meeting: N/A

Wagner (December 29, 2021/January 27, 2022)
All-Time Series: Wagner leads 49-24
Record vs Wagner at home: Saint Francis leads 26-9
Record vs. Wagner on the road: Saint Francis leads 19-15
Current Streak: Wagner won 2
First Meeting: Saint Francis (85-49) 1984-85
Last Meeting: Wagner (70-57) 2020-21
Last Saint Francis Win: (51-50) 2019-20

Fairleigh Dickinson (December 31, 2021/February 11, 2022)
All-Time Series: Saint Francis leads 46-23
Record vs Fairleigh Dickinson at home: Saint Francis leads 26-9
Record vs. Fairleigh Dickinson on the road: Saint Francis leads 20-14
Current Streak: Saint Francis won 2
First Meeting: Saint Francis (75-62) 1954-55
Last Meeting: Saint Francis (64-48) 2020-21
Last Fairleigh Dickinson Win: (56-47) 2019-20

St. Francis Brooklyn (January 6, 2022/February 19, 2022)
All-Time Series: Saint Francis leads 47-19
Record vs St. Francis Brooklyn at home: Saint Francis leads 27-6
Record vs. St. Francis Brooklyn on the road: Saint Francis leads 20-13
Current Streak: Saint Francis won 1
First Meeting: Saint Francis (90-72) 1985-86
Last Meeting: Saint Francis Brooklyn (63-55) 2020-21
Last Saint Francis Win: (56-55) 2020-21

Long Island (January 8, 2022/February 17, 2022)
All-Time Series: Saint Francis leads 50-20
Record vs Long Island at home: Saint Francis leads 28-7
Record vs. Long Island on the road: Saint Francis leads 18-13
Current Streak: Saint Francis won 2
First Meeting: Saint Francis (96-57) 1985-86
Last Meeting: Saint Francis (66-62) 2020-21
Last Long Island Win: (71-64) 2019-20

Merrimack (January 15, 2022/February 5, 2022)
All-Time Series: Saint Francis leads 2-1
Record vs Merrimack at home: Saint Francis leads 2-1
Record vs. Merrimack on the road: Series tied 0-0
Current Streak: Saint Francis won 2
First Meeting: Merrimack (71-56) 2019-20
Last Meeting: Saint Francis (61-48) 2020-21
Last Merrimack Win: (71-56) 2019-20

Bryant (January 17, 2022/February 3, 2022)
All-Time Series: Saint Francis leads 14-9
Record vs Bryant at home: Saint Francis leads 6-2
Record vs. Bryant on the road: Bryant leads 7-3
Current Streak: Saint Francis won 5
First Meeting: Saint Francis (80-75) 2008-09
Last Meeting: Saint Francis (66-62) 2020-21
Last Bryant Win: (66-63) 2018-19

Central Connecticut State (January 21, 2022/February 24, 2022)
All-Time Series: Saint Francis leads 33-13
Record vs Central Connecticut State at home: Saint Francis leads 19-4
Record vs. Central Connecticut State on the road: Saint Francis leads 13-8
Current Streak: Saint Francis won 5
First Meeting: Central Connecticut State (70-67) 1997-98
Last Meeting: Saint Francis (69-62) 2020-21
Last Central Connecticut State Win: (73-62) 2018-19

Sacred Heart (January 23, 2022/February 26, 2022)
All-Time Series: Sacred Heart leads 26-19
Record vs Sacred Heart at home: Saint Francis leads 13-10
Record vs. Sacred Heart on the road: Sacred Heart leads 16-6
Current Streak: Sacred Heart won 1
First Meeting: Saint Francis (65-49) 1999-00
Last Meeting: Saint Francis (72-67 ot) 2020-21
Last Sacred Heart Win: (76-70 ot) 2020-21

Mount St. Mary's (January 29, 2022/March 3, 2022)
All-Time Series: Saint Francis leads 35-32
Record vs Mount St. Mary's at home: Saint Francis leads 21-10
Record vs. Mount St. Mary's on the road: Mount St. Mary's leads 22-14
Current Streak: Mount St. Mary's won 2
First Meeting: Mount St. Mary's (82-66) 1988-89
Last Meeting: Mount St. Mary's (71-55)
Last Saint Francis Win: (83-72) 2018-19